- USA
- South Carolina
- Cowpens
- Mayo
- Rentals by Owner
Find Your Ideal Rental by Owner in Mayo, South Carolina for a Seamless Vacation Experience
Discover Your Perfect Mayo Rentals by Owner
-
Rentals by Owner
-
Luxury Vacation Rentals
-
Pet Friendly Vacation Rentals
-
Unique Vacation Rentals
-
Cabin Rentals
-
Cottage Rentals
-
Ski Chalet Rentals
-
Timeshares
-
Villa Rentals
-
Hotels with Suites
-
Resort Rentals
-
Family Vacation Rentals
-
Vacation Rentals with Pools
-
Oceanfront Vacation Rentals
-
Beach House Rentals
-
Summer Vacation Rentals
-
Winter Vacation Rentals
-
Short Term Rentals
-
Corporate Accommodation
-
Large Group Vacation Rentals
-
Sustainable Travel
Mayo Rentals by Owner
- Air Conditioner
- Parking
- Pet Friendly
- Air Conditioner
- Parking
- Security/Safety
- Air Conditioner
- Parking
- Pet Friendly
- Air Conditioner
- Parking
- TV
- Air Conditioner
- Security/Safety
- Fireplace/Heating
- Air Conditioner
- Parking
- TV
- Air Conditioner
- Parking
- TV
- Air Conditioner
- Parking
- Pet Friendly
- Air Conditioner
- Parking
- TV
- Air Conditioner
- Parking
- Pet Friendly
- Air Conditioner
- TV
- Balcony/Terrace
- Air Conditioner
- Security/Safety
- Child Friendly
Why Choose Rent By Owner for your Mayo vacation rental?
What makes our Rentals by Owner special?
Best Times to Visit Mayo
When should you plan your Rentals by Owner stay?
To make the most of your stay, consider visiting during the region's optimal seasons, when the weather is ideal and local events align, ensuring a memorable vacation experience in Mayo, South Carolina, USA.
Peak Season Highlights
Spring (March to May)
During spring, the region sees an influx of visitors seeking mild weather and blooming landscapes, making it an ideal time for outdoor activities and exploring local attractions.
Summer (June to August)
Summer is the most popular time to visit, with warm temperatures perfect for enjoying the area’s natural beauty and participating in outdoor pursuits.
Off-Season Highlights
Fall (September to November)
Traveling during fall offers cooler temperatures and fewer crowds, providing a peaceful setting to enjoy the natural scenery and vibrant foliage.
Winter (December to February)
The winter months bring lower visitor numbers, making it an excellent choice for those seeking quiet accommodations and a more relaxed experience here.
Weekly Weather Forecast for Mayo
How to Book Your Mayo vacation rental
What's our booking process?
Booking Steps
Search Properties
Select a Rental
Book Online
Explore and book the perfect rental in Mayo
Common Rentals by Owner Amenities
What amenities can you expect?
Indoor Features
- Fully-equipped kitchens with modern appliances
- Comfortable living areas with flat-screen TVs
- Free Wi-Fi for staying connected
- Air conditioning and heating for year-round comfort
- In-unit washers and dryers for convenience
- Luxurious bedrooms with premium bedding
- Spa-like bathrooms with soaking tubs or walk-in showers
Outdoor Amenities
- Enjoy a private outdoor patio or deck for relaxing and dining al fresco.
- Take advantage of spacious yards or gardens perfect for outdoor activities or gatherings.
- Make the most of swimming pools or hot tubs available on the property to unwind and refresh.
- Explore scenic views from outdoor seating areas designed to highlight the region’s natural beauty.
- Utilize barbecue grills for outdoor cooking and hosting memorable cookouts with family and friends.
- Benefit from shaded areas or pergolas that provide comfortable spots to enjoy the fresh air.
- Access nearby outdoor amenities such as walking trails or picnic spots within a short drive in this destination’s region.
Top Attractions Around Mayo
What attractions are nearby?
In this charming area, you can enjoy a variety of outdoor activities such as fishing, boating, and exploring scenic nature trails, all conveniently accessible from your rental by owner in Mayo, South Carolina.

Family Activities
- South Carolina Maritime Museum: Discover local history and maritime heritage through engaging exhibits suited for the whole family.
- Backwater Adventure Tours: Experience the region’s natural beauty with guided eco-tours that highlight the area's unique coastal ecosystems.
- Sea Island Nature Center: Explore scenic walking trails and enjoy educational programs focused on the region's rich wildlife and habitat.
- Local Family Parks and Playgrounds: Relax and have fun at well-maintained parks offering playgrounds, picnic areas, and open spaces for outdoor activities.
Adult Activities
- Guided Nature Tours: Explore the scenic landscapes of this destination by joining guided tours that showcase the area's natural beauty and wildlife.
- Local Craft Breweries: Visit the region's craft breweries to enjoy local brews and learn about the area's brewing heritage in a relaxed setting.
- Historic Site Visits: Immerse yourself in the region’s history by touring historic sites that offer insights into its rich cultural background.
- Fishing Excursions: Take part in fishing trips along the area’s waterways, perfect for relaxing and enjoying the outdoors in this destination.
Mayo Travel Tips
How Can You Make the Most of Your Stay?
- Plan Ahead for Local Experiences: Research nearby outdoor activities and community events to fully immerse yourself in the region's natural beauty and local culture.
- Choose a Rental with Scenic Views: Select a vacation rental by owner that offers picturesque views of the surrounding landscape to enhance your stay.
- Utilize Local Resources: Take advantage of information provided by your host or the area’s visitor centers to discover hidden gems and authentic dining options.
- Respect the Community and Environment: Follow local guidelines and be mindful of the natural environment to enjoy a sustainable and respectful visit here.
Transportation Options
- Driving via Personal Vehicles: With well-maintained roads, your own car offers the most flexible way to explore the region around Mayo and access nearby attractions at your convenience.
- Rental Cars: Numerous rental agencies serve this area, providing a reliable option for visitors who prefer driving themselves during their stay.
- Local Bus Services: Public buses operate within the region, offering an affordable way to get around and connect to nearby towns and amenities.
- Taxi and Rideshare Services: Taxis and popular rideshare options are available here, ensuring easy transportation without the need for personal vehicle ownership.
Local Customs Options
- Southern Hospitality: You can expect a warm and welcoming attitude from locals who take pride in their southern hospitality here in Mayo.
- Community Events: Participating in local festivals and neighborhood gatherings offers an authentic glimpse into the region’s friendly customs.
- Farm-to-Table Dining: Supporting local farmers and enjoying fresh, regional cuisine is a cherished tradition you’ll find throughout this area.
- Respect for Nature: Appreciating the natural surroundings by engaging in outdoor activities and observing conservation practices reflects the region’s deep connection to its environment.
Frequently Asked Questions About Mayo Rentals by Owner
1. What are the top vacation rentals in Mayo?
There are a lot of options in Mayo. If you plan on staying in the Mayo area, consider making a reservation for a few nights at one of these properties as these have been rated the Top Vacation Rentals in Mayo:
- New duplex; sleeps 6! Pet friendly! Perfect for traveling medical and families!
- Serene Country Cabin. 30 min from TIEC, FENCE, hiking, & Spartanburg.
- Charming 1-bedroom house with WiFi and AC in Cowpens
- Remodeled 3 bed, 2 bath in Cowpens, SC. Near Gaffney, Spartanburg, Charlotte
- Duplex in Boiling Springs, SCnn
- Cozy Home off I-85, 35 minutes from NC and SC border
- Charming 3-bedroom house with games and karaoke in lovely Boiling Springs
- 88-acre w/Lodge, pavilion, and lake in SC! Sit back and relax at VSL!
- Great private home in convenient location
- Peach Haven Hideaway
2. How many Rentbyowner vacation rentals are available in Mayo?
Currently, the total number of properties listed by Rent By Owner in 2025 is over 21 in the Mayo area, and still counting. By aggregating listings from multiple websites, Rent By Owner offers an immense amount of choice of the best RBO properties in Mayo.
3. What is the cancellation policy for a rental by owner in Mayo, South Carolina?
4. How can I confirm the availability of a vacation home in Mayo, South Carolina?
5. Are there any additional fees associated with booking a rental by owner in Mayo, South Carolina?
6. What amenities are typically included in rentals by owner in Mayo, South Carolina?
7. How do I ensure that my booking with a rental owner in Mayo, South Carolina, is secure?
More Rentals You May Like Near Mayo
- Air Conditioner
- Parking
- TV
- Air Conditioner
- Parking
- TV
- Air Conditioner
- Parking
- TV
- Air Conditioner
- TV
- Bedding/Linens
- Child Friendly
- Internet
- Kitchen
- Air Conditioner
- TV
- Bedding/Linens
- Air Conditioner
- Bedding/Linens
- Child Friendly