Discover Your Perfect Jefferson County Vacation Homes

Best Vacation Homes in Jefferson County

Cabin
Map-icon
like-icon10.0
Exceptional
(189 Reviews)
5 Bedrooms 3 Baths 18 Guests 4000 ft²
  • Private Pool
    Private Pool
  • Hot Tub
    Hot Tub
More amenities
AU $878/Night 7 Nights - AU $6,147
House
Map-icon
like-icon10.0
Exceptional
(1 Review)
2 Bedrooms 1 Bath 4 Guests 904.17 ft²
  • Fireplace/Heating
    Fireplace/Heating
  • Parking
    Parking
More amenities
AU $201/Night 7 Nights - AU $1,404
star-icons-3
Hotel
Map-icon
like-icon9.6
Exceptional
(1694 Reviews)
1 Bath
  • Hot Tub
    Hot Tub
  • Pool
    Pool
More amenities
AU $173/Night 7 Nights - AU $1,212
House
Map-icon
like-icon10.0
Exceptional
(36 Reviews)
1 Bedroom 1 Bath 3 Guests 625 ft²
  • Fireplace/Heating
    Fireplace/Heating
  • Balcony/Terrace
    Balcony/Terrace
More amenities
AU $139/Night 7 Nights - AU $975
star-icons-3
Hotel
Map-icon
like-icon9.5
Exceptional
(1093 Reviews)
25 Baths 344.01 ft²
  • Hot Tub
    Hot Tub
  • Fireplace/Heating
    Fireplace/Heating
More amenities
AU $220/Night 7 Nights - AU $1,539
Apartment
Map-icon
like-icon10.0
Exceptional
(15 Reviews)
1 Bedroom 1 Bath 6 Guests 1020 ft²
  • Fireplace/Heating
    Fireplace/Heating
  • Kitchen
    Kitchen
More amenities
AU $222/Night 7 Nights - AU $1,553
House
Map-icon
like-icon10.0
Exceptional
(7 Reviews)
2 Bedrooms 1 Bath 4 Guests 1600 ft²
  • Fireplace/Heating
    Fireplace/Heating
  • Balcony/Terrace
    Balcony/Terrace
More amenities
AU $264/Night 7 Nights - AU $1,851
House
Map-icon
like-icon10.0
Exceptional
(1 Review)
2 Bedrooms 1 Bath 4 Guests 900 ft²
  • Fireplace/Heating
    Fireplace/Heating
  • Balcony/Terrace
    Balcony/Terrace
More amenities
AU $185/Night 7 Nights - AU $1,295

Jefferson County Luxury Rentals

Hotel
Map-icon
like-icon7.1
Very Good
(11 Reviews)
6 Baths 3336.81 ft²
  • Fireplace/Heating
    Fireplace/Heating
  • Pet Friendly
    Pet Friendly
More amenities
AU $690/Night 7 Nights - AU $4,831
star-icons-4
Hotel
Map-icon
like-icon7.2
Very Good
(193 Reviews)
1 Bath
  • Private Pool
    Private Pool
  • Oceanfront
    Oceanfront
More amenities
AU $663/Night 7 Nights - AU $4,638
House
Map-icon
like-icon9.4
Exceptional
(3 Reviews)
5 Bedrooms 2 Baths 10 Guests
  • Fireplace/Heating
    Fireplace/Heating
  • Balcony/Terrace
    Balcony/Terrace
More amenities
AU $289/Night 7 Nights - AU $2,021
House
Map-icon
like-icon9.4
Exceptional
(19 Reviews)
3 Bedrooms 2 Baths 6 Guests
  • Fireplace/Heating
    Fireplace/Heating
  • Balcony/Terrace
    Balcony/Terrace
More amenities
AU $260/Night 7 Nights - AU $1,819
House
Map-icon
like-icon6.0
Good
(1 Review)
4 Bedrooms 2 Baths 15 Guests
  • Fireplace/Heating
    Fireplace/Heating
  • Air Conditioner
    Air Conditioner
More amenities
AU $243/Night 7 Nights - AU $1,700
House
Map-icon
like-icon5.4
Average
(3 Reviews)
2 Bedrooms 1 Bath 6 Guests
  • Fireplace/Heating
    Fireplace/Heating
  • Balcony/Terrace
    Balcony/Terrace
More amenities
AU $210/Night 7 Nights - AU $1,467
House
Map-icon
like-icon9.0
Exceptional
(37 Reviews)
2 Bedrooms 1 Bath 5 Guests
  • Fireplace/Heating
    Fireplace/Heating
  • Balcony/Terrace
    Balcony/Terrace
More amenities
AU $201/Night 7 Nights - AU $1,405
star-icons-4
Hotel
Map-icon
like-icon8.4
Excellent
(817 Reviews)
1 Bath
  • Fireplace/Heating
    Fireplace/Heating
  • Pool
    Pool
More amenities
AU $199/Night 7 Nights - AU $1,393

Jefferson County Pet Friendly Vacation Rentals

Cabin
Map-icon
like-icon9.6
Exceptional
(27 Reviews)
2 Bedrooms 1 Bath 5 Guests
  • Fireplace/Heating
    Fireplace/Heating
  • Balcony/Terrace
    Balcony/Terrace
More amenities
AU $149/Night 7 Nights - AU $1,044
star-icons-3
Hotel
Map-icon
like-icon8.8
Fabulous
(612 Reviews)
7 Baths 364.44 ft²
  • Private Pool
    Private Pool
  • Hot Tub
    Hot Tub
More amenities
AU $186/Night 7 Nights - AU $1,306
Cabin
Map-icon
like-icon9.2
Exceptional
(123 Reviews)
2 Bedrooms 1 Bath 7 Guests 900 ft²
  • Hot Tub
    Hot Tub
  • Fireplace/Heating
    Fireplace/Heating
More amenities
AU $89/Night 7 Nights - AU $625
star-icons-3
Hotel
Map-icon
like-icon7.2
Very Good
(678 Reviews)
4 Baths 269.1 ft²
  • Fireplace/Heating
    Fireplace/Heating
  • Breakfast
    Breakfast
More amenities
AU $106/Night 7 Nights - AU $744
House
Map-icon
2 Bedrooms 1 Bath 4 Guests 680 ft²
  • Fireplace/Heating
    Fireplace/Heating
  • Balcony/Terrace
    Balcony/Terrace
More amenities
AU $88/Night 7 Nights - AU $613
star-icons-3
Hotel
Map-icon
like-icon6.6
Good
(123 Reviews)
10 Baths 204.51 ft²
  • Fireplace/Heating
    Fireplace/Heating
  • Pet Friendly
    Pet Friendly
More amenities
AU $97/Night 7 Nights - AU $678
Hotel
Map-icon
like-icon6.5
Good
(66 Reviews)
5 Baths 27.99 ft²
  • Fireplace/Heating
    Fireplace/Heating
  • Pet Friendly
    Pet Friendly
More amenities
AU $94/Night 7 Nights - AU $658
Hotel
Map-icon
like-icon6.1
Good
(207 Reviews)
7 Baths 336.76 ft²
  • Fireplace/Heating
    Fireplace/Heating
  • Pool
    Pool
More amenities
AU $112/Night 7 Nights - AU $781

Jefferson County Large Vacation Homes

Cabin
Map-icon
6 Bedrooms 3 Baths 20 Guests 4000 ft²
  • Private Pool
    Private Pool
  • Oceanfront
    Oceanfront
More amenities
AU $3,672/Night 7 Nights - AU $25,705

Why Choose Rent By Owner for your Jefferson County Vacation Rental Homes?

What makes our Vacation Rentals special?

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Verified Listings
Book with confidence knowing every property meets our quality and safety standards.
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Unbeatable Value
Enjoy competitive pricing with no hidden fees, providing exceptional value for every stay.
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Diverse Options
From cozy cabins to luxurious villas, find a rental that suits your style and needs.

Best Times to Visit Jefferson County

When should you plan your Vacation Rentals stay?

Choosing the right time to vacation here can enhance your experience, allowing you to enjoy the region’s unique climate and outdoor activities at their best.

Peak Season Highlights

summer
Late Spring to Early Summer (May to June)

During this time, you can enjoy warm weather and longer days, making it ideal for exploring outdoor activities in the region.

Average Temperature Daytime: 75°F to 85°F - Nighttime: 55°F to 65°F
autumn
Early Fall (September to October)

This season offers pleasant temperatures and fewer crowds, perfect for relaxing stays and scenic drives around the area.

Average Temperature Daytime: 70°F to 80°F - Nighttime: 50°F to 60°F

Off-Season Highlights

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Winter (December to February)

Experience quieter accommodations during the colder months when outdoor activities are limited but the region offers cozy retreats and scenic winter views.

Average Temperature Daytime: 30°F to 45°F - Nighttime: 15°F to 30°F
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Late Fall (November)

With cooler temperatures and falling leaves, this is a peaceful period to enjoy the area's natural beauty without the peak-season crowds.

Average Temperature Daytime: 45°F to 55°F - Nighttime: 35°F to 45°F

Weekly Weather Forecast for Jefferson County

Booking Steps

01

Search Properties

Use our filters to find the right property that fits your needs.
02

Select a Rental

Click on your preferred listing to view details, amenities, and pricing.
03

Book Online

Follow the link to finalize your reservation directly on the partner’s website.

Indoor Features

  • Fully-equipped kitchens with modern appliances
  • Comfortable living areas with flat-screen TVs
  • Free Wi-Fi for staying connected
  • Air conditioning and heating for year-round comfort
  • In-unit washers and dryers for convenience
  • Luxurious bedrooms with premium bedding
  • Spa-like bathrooms with soaking tubs or walk-in showers

Outdoor Amenities

  • Enjoy outdoor activities with access to spacious yards or gardens at your vacation rental in the region.
  • Take advantage of private patios or decks perfect for relaxing or dining al fresco in this area.
  • Make the most of nearby parks and green spaces for picnicking, walking, or outdoor recreation.
  • Utilize outdoor grilling facilities to prepare meals while enjoying the fresh air here.
  • Relax by a private or community swimming pool available at many vacation rentals in the region.
  • Experience outdoor entertainment options such as fire pits or campfire areas suitable for gatherings.
  • Access scenic views and outdoor photo opportunities that showcase the natural beauty of this destination.
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Family Activities

  • Fort de Chartres Cultural Site: Explore this historic French fort to immerse your family in the region's rich history and enjoy engaging guided tours.
  • Experience scenic boat cruises along the mighty Mississippi River, offering fantastic views and family-friendly excursions in the area.
  • Giant City State Park: Discover outdoor adventures with hiking trails, rock formations, and picnic areas that make for memorable family outings here.
  • Karbers Ridge Historic District: Visit this charming district to explore preserved buildings and enjoy a leisurely day learning about local heritage together.
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Adult Activities

  • Visit the Jefferson County Historical Village: immerse yourself in local history through engaging exhibits and preserved buildings that tell the story of this area's rich past.
  • Explore the Crab Orchard National Wildlife Refuge: enjoy the region’s natural beauty by birdwatching, hiking, or wildlife photography within this expansive sanctuary.
  • Tour the local wineries and breweries: sample regional flavors at nearby wineries and breweries, offering a taste of the area's growing craft beverage scene.
  • Attend seasonal festivals and events: participate in community celebrations and festivals throughout the year that showcase local culture and traditions here in the region.

Jefferson County Travel Tips

How Can You Make the Most of Your Stay?

  • Plan Ahead with Local Events: Check the area's event calendar to align your stay with local festivals or markets, enhancing your experience in this charming destination.
  • Explore Nearby Natural Attractions: Take advantage of the region's outdoor spaces by scheduling time for scenic hikes or leisurely walks through nearby parks and trails.
  • Choose Strategic Accommodation Locations: Select vacation rentals close to key attractions or central areas to maximize your sightseeing and minimize travel time within the region.
  • Engage with Local Culture: Immerse yourself in local traditions and eateries, making your visit more authentic and memorable during your stay here.

Transportation Options

  • Jefferson County Transit Service: This local bus system provides convenient transportation within the area, making it easy to explore nearby attractions and amenities.
  • Amtrak Station in Mount Vernon: Connecting travelers to major cities across the country, the Amtrak station offers a reliable rail option for those looking to travel beyond the region.
  • Regional Airport (St. Louis Lambert International Airport): Located a short drive away, this airport offers extensive domestic flights, providing seamless access to and from here for your vacation plans.
  • Rental Car Services: Numerous rental agencies operate in the area, giving you flexible transportation options to explore Jefferson County and its surroundings at your own pace.

Local Customs Options

  • Gospel Music Tradition: In this region, gospel music holds a special place, and you might find local churches celebrating their rich musical heritage through lively performances.
  • Harvest Festivals: Participating in seasonal harvest festivals offers a glimpse into the area's agricultural roots and community-centered traditions.
  • Historical Preservation: Respect for historical sites and architecture is prevalent here, making it common to see locals engaging in preservation efforts of their town’s heritage.
  • The area honors its history with memorials dedicated to Civil War veterans, providing insight into the region's historical significance.

Frequently Asked Questions About Jefferson County?

2. Which vacation homes in Jefferson County are best for families?

If you are looking for a family-friendly vacation home in Jefferson County, check out one of the following properties as all are highly-rated places to stay with excellent review for families or groups staying in Jefferson County:

3. How many Rentbyowner vacation rentals are available in Jefferson County?

Currently, the total number of properties listed by Rent By Owner in 2026 is over 42 in the Jefferson County area, and still counting. By aggregating listings from multiple websites, Rent By Owner offers an immense amount of choice of the best RBO properties in Jefferson County. 

4. What is the cancellation policy for vacation rentals in this area?

Cancellation policies vary by property, so you should review the specific listing details or contact the owner directly to understand the terms and any applicable fees before booking.

5. Are there specific check-in and check-out times for vacation rentals here?

Check-in and check-out times are set by each property owner. Please refer to the individual listing for this information or reach out to the host for confirmation.

6. How do I find pet-friendly vacation rentals in this region?

Pet-friendly options are available, but they are listed with specific filters on the booking platform. It's best to verify pet policy details directly within the listing or communicate with the owner.

7. What amenities are typically included in vacation rentals around here?

Amenities can differ from one property to another, so you'll want to review each listing's amenities section or contact the owner to ensure your needs are met during your stay.

8. How can I ensure my booking is secure and reliable?

Use trusted platforms that verify property listings and provide secure payment options. Always read reviews and communicate through the official messaging system to confirm details before finalizing your reservation.

Jefferson County Top Rated Vacation Rentals

Hotel
Map-icon
like-icon9.0
Exceptional
(1028 Reviews)
1 Bath
  • Hot Tub
    Hot Tub
  • Pool
    Pool
More amenities
AU $176/Night 7 Nights - AU $1,231
Hotel
Map-icon
like-icon9.0
Exceptional
(1006 Reviews)
1 Bath
  • Pool
    Pool
  • Balcony/Terrace
    Balcony/Terrace
More amenities
AU $178/Night 7 Nights - AU $1,245
star-icons-3
Hotel
Map-icon
like-icon8.8
Fabulous
(698 Reviews)
1 Bath
  • Pool
    Pool
  • Breakfast
    Breakfast
More amenities
AU $185/Night 7 Nights - AU $1,297
star-icons-3
Hotel
Map-icon
like-icon8.7
Fabulous
(230 Reviews)
12 Baths 301.39 ft²
  • Private Pool
    Private Pool
  • Oceanfront
    Oceanfront
More amenities
AU $168/Night 7 Nights - AU $1,176
star-icons-3
Hotel
Map-icon
like-icon8.1
Excellent
(84 Reviews)
9 Baths 3950.35 ft²
  • Private Pool
    Private Pool
  • Oceanfront
    Oceanfront
More amenities
AU $162/Night 7 Nights - AU $1,134
Hotel
Map-icon
like-icon6.6
Good
(1003 Reviews)
1 Bath
  • Pool
    Pool
  • Breakfast
    Breakfast
More amenities
AU $114/Night 7 Nights - AU $795
Hotel
Map-icon
like-icon8.8
Fabulous
(667 Reviews)
1 Bath
  • Fireplace/Heating
    Fireplace/Heating
  • Pool
    Pool
More amenities
AU $173/Night 7 Nights - AU $1,210